Cathodic action potentials may block centrally at high current, explaining polarity effects
Evidence
While at hearing threshold, no consistent difference between polarities has been observed, a large number of studies have reported that anodic stimulation is more effective than cathodic stimulation at suprathreshold levels (Macherey et al. 2006 , 2008 ; Undurraga et al. 2013 ; Carlyon et al. 2013 ). — Dijk, Pim van, Physiology, Psychoacoustics and…, 2275 (
#contradicts, via linked claim)
Categorization
- corroborated: 3 independent passages support this claim
- XREF: connects to: Some cathodic responses decrease as current rises, growing non-monotonically; Anodic stimulation exceeds cathodic at suprathreshold levels in human CI users; Anodic current outperforms cathodic current in human cochlear implant users at suprathreshold levels — Dijk, Pim van, Physiology, Psychoacoustics and…, 2275 (+2 more)
Related
- Some cathodic responses decrease as current rises, growing non-monotonically (similarity 0.93)
- Anodic current outperforms cathodic current in human cochlear implant users at suprathreshold levels (similarity 0.92)
- Cathodic pulses evoke larger inferior colliculus responses than anodic pulses (similarity 0.91)
- Cathodic pulse superiority holds across all four tested pulse shapes (similarity 0.91)
- Anodic stimulation exceeds cathodic at suprathreshold levels in human CI users (similarity 0.88)
- Cathodic pulses produce larger cochlear implant responses than anodic pulses across pulse shapes (similarity 0.87)
- Anodic and cathodic cochlear implant stimulation differ in efficiency between humans and animals (similarity 0.87)
- At high current a cathodic pulse can block its own action potentials centrally. (similarity 0.87)
- Never degeneration of neural peripheral processes may explain human anodic stimulation preference (similarity 0.87)
- Pulse polarity effects on neural response differ significantly across pulse shapes (similarity 0.85)
- Cathodic current pulses produce larger neural responses than anodic ones (similarity 0.85)
- Cochlear implant input-output responses can reverse polarity preference at high levels (similarity 0.85)
- Cathodic pulses are more efficient in animals but anodic pulses in humans (similarity 0.84)
- Anodic stimulation is more effective in human implant users but less effective in animals (similarity 0.84)
- Action potential blocking for cathodic stimuli would produce non-monotonic neural growth patterns. (similarity 0.82)
Broader Connections
- Some cathodic responses decrease as current rises, growing non-monotonically
#corroborates(0.85) - Anodic stimulation exceeds cathodic at suprathreshold levels in human CI users
#contradicts(0.80) - Anodic current outperforms cathodic current in human cochlear implant users at suprathreshold levels
#contradicts(0.80) — Dijk, Pim van, Physiology, Psychoacoustics and…, 2275 - Pulse polarity effects on neural response differ significantly across pulse shapes
#qualifies(0.75) - Cathodic pulses evoke larger inferior colliculus responses than anodic pulses
#contradicts(0.72) — Dijk, Pim van, Physiology, Psychoacoustics and…, 2272