The olivo-cochlear efferent system accelerates recovery from calcium-induced sensitivity changes.

Evidence

In contrast, the slow efferent effect (Sridhar et al. 1997 ) can cause a constant Ca2+ release from OHC internal stores, the lateral cisternae, while CAS is on. We hypothesize that this constant influx of Ca2+ may help to accelerate Ca2+ -dependent Ca2+ -uptake and thus, a quicker recovery of the system. In summary, the current experiments reveal a pronounced effect of LF exposure on the active mechanisms in the inner ear, as they are mediated by OHCs. — Dijk, Pim van, Physiology, Psychoacoustics and…, 3744

Categorization

• QUESTION: The mechanism linking constant Ca2+ release to accelerated reuptake is hypothesized, not demonstrated — worth checking for subsequent confirmation.
• corroborated: 2 independent passages support this claim — Dijk, Pim van, Physiology, Psychoacoustics and…, 3744
• XREF: connects to: An acoustic reflex desensitizes the ear to protect cochlear hair cells; Calcium oscillations in outer hair cells drive the hearing Bounce; Brainstem efferent signals shorten the hearing Bounce (+4 more)

Broader Connections

• Low-frequency sound’s after-effects arise from calcium homeostasis in outer hair cells #expands (0.82) — Dijk, Pim van, Physiology, Psychoacoustics and…, 3701