Resting-state connectivity analysis must filter physiological noise that inflates correlations

Evidence

At low frequencies it is assumed that the subject produces his/her own noise as a consequence of the blood supply in the inner ear and of vibrations produced by the heart and muscles. We adapt to this noise because it is always there and therefore we don’t usually hear it, particularly in our normal surroundings. This kind of internal noise is especially strong at low frequencies. At medium and high frequencies there may be noise produced in the neural processing. — Professor Dr.-Ing. Hugo Fastl, Professor Dr.-Ing. Eberhard, Psychoacoustics- Facts and Models, 1148 (#expands, via linked claim)

Categorization

• corroborated: 3 independent passages support this claim
• XREF: connects to: fMRI measures slow metabolic changes and is noisy, complicating auditory research; Resting-state fMRI reveals connectivity differences in numerous brain regions in tinnitus. — Dijk, Pim van, Physiology, Psychoacoustics and…, 2707; Resting-state connectivity reflects neural plasticity from deafness and reorganisation — Dijk, Pim van, Physiology, Psychoacoustics and…, 4273 (+1 more)

Broader Connections

• Internal physiological noise from blood flow and heartbeat raises low-frequency thresholds #expands (0.80) — Professor Dr.-Ing. Hugo Fastl, Professor Dr.-Ing. Eberhard, Psychoacoustics- Facts and Models, 1148