Physiological noise like heartbeat and breathing can masquerade as neural connectivity
Evidence
Since resting state connectivity is based upon correlations between activity in relevant channels, it is important to carefully remove any aspects of the data (such as fluctuations from heartbeat, breathing, or from movement artifacts that are present in all channels) that would produce a correlation but is not related to neural activity. — Dijk, Pim van, Physiology, Psychoacoustics and…, 4287
Categorization
Category: Causal Relationships
- XREF: Connects to the broader caution about correlational measures in neuroimaging; also relevant to how any correlation-based connectivity metric must control for shared global signals.
Related
- Resting-state connectivity measures risk spurious correlations from global artifacts (similarity 0.96)
- Correlations between brain regions require removal of shared physiological noise. (similarity 0.89)
- Resting-state connectivity analysis must filter physiological noise that inflates correlations (similarity 0.86)
- Resting-state connectivity reflects the brain’s predictive ability and plasticity (similarity 0.80)
- Resting-state connectivity reflects neural plasticity from deafness and reorganisation (similarity 0.78)