Action-potential blocking along nerve fibers may explain anodic stimulation advantage at higher levels

Evidence

In few cases, input/output growth functions were non-monotonic, showing a decrease in response amplitude with increases in level. Similar non-monotonic functions have already been observed at the level of the auditory nerve (Miller et al. 1998 ). They may reflect the blocking of action potentials along the nerve fibers (Frijns et al. 1996 ) and, therefore, remain a possible candidate explanation for the higher efficiency of anodic stimulation at suprathreshold levels in humans. — Dijk, Pim van, Physiology, Psychoacoustics and…, 2272