Prenatal famine exposure among Leningrad Siege survivors produces fetal programming effects transmitted to descendants, likely via epigenetic mechanisms.

Evidence

Transgenerational and intergenerational effects of early childhood famine exposure in the cohort of offspring of Leningrad Siege survivors (Scientific Reports (Nature))

Categorization

• corroborated: 2 independent passages support this claim
• XREF: connects to: Extreme misfortune can have cascading negative effects on families. — Crews, Harry, A childhood the biography of a place, 21; Technophysio evolution describes how technology and nutrition advances drove intergenerational rises in human height over the last century, independent of genetic change. — A theory of technophysio evolution, with some implications for forecasting population, health care costs, and pension costs; Parental exposure to genocide-related trauma is associated with altered caregiving patterns—overprotection, controlling behavior, diminished warmth—affecting subsequent generations. — Epigenetic changes associated with multi-generational trauma (+5 more)

Related

• Parental exposure to genocide-related trauma is associated with altered caregiving patterns—overprotection, controlling behavior, diminished warmth—affecting subsequent generations. (similarity 0.83)
• Offspring of trauma survivors show stress biological changes without direct exposure (similarity 0.79)

Broader Connections

• Historical trauma transmits across generations through grief and disrupted cultural transmission #expands (0.60) — , The Rod and the Child, 10692
• Different adversities alter brain regions matched to the developmental stage of harm #qualifies (0.40) — , The Rod and the Child, 9655