High ACE scores predict a 31-fold rise in lifetime suicide attempts

Evidence

ACE score 7 or above associated with a 31-fold increase in attempted suicide compared to ACE score zero, with the relationship partially mediated through adolescent depression and substance abuse. The paper’s findings contribute directly to the intergenerational circuit argument: by documenting that high-ACE adults disproportionately carry the psychiatric sequelae — depression, substance use, chronic dysregulation — that constitute ACE categories seven (mental illness in household) and six (substance abuse in household) for the next generation, it provides quantitative weight to the indirect-transmission pathway. — , The Rod and the Child, 10673

Categorization

• XREF: The 31-fold figure and the closed-loop transmission argument connect directly to the ACE pyramid feedback loop developed in E109. — connects to: High-ACE parents generate high-ACE environments for their children within a single practice — , The Rod and the Child: A Global History…, 7084; Each additional ACE point raises risk of major adult diseases in graded fashion. — , The Rod and the Child: A Global History…, 9506; Childhood adversity dose predicts adult depression, alcoholism, and suicide attempts — , The Rod and the Child: A Global History…, 10671

Related

• Childhood adversity dose predicts adult depression, alcoholism, and suicide attempts (similarity 0.89)
• Each additional ACE point raises risk of major adult diseases in graded fashion. (similarity 0.88)
• Six ACE categories are themselves outcomes of parents’ own high ACE scores. (similarity 0.84)
• ACE dose-response effects strengthen with higher baseline adversity in other populations (similarity 0.83)
• High-ACE parents generate high-ACE environments for their children within a single practice (similarity 0.83)
• The ACE pyramid is a self-reinforcing intergenerational circuit, not a linear diagram. (similarity 0.79)

Broader Connections

• Childhood adversity dose predicts adult depression, alcoholism, and suicide attempts #corroborates (0.85) — , The Rod and the Child, 10671