Deconvolving the eCAP reveals two separate auditory nerve firing components.

Evidence

The electrically evoked compound action potential (eCAP) is a routinely performed measure of the auditory nerve in cochlear implant users. Using a convolution model of the eCAP, additional information about the neural firing properties can be obtained, which may provide relevant information about the health of the auditory nerve. In this study, guinea pigs with various degrees of nerve degeneration were used to directly relate firing properties to nerve histology. The same convolution model was applied on human eCAPs to examine similarities and ultimately to examine its clinical applicability. For most eCAPs, the estimated nerve firing probability was bimodal and could be parameterised by two Gaussian distributions with an average latency difference of 0.4 ms. — Dijk, Pim van, Physiology, Psychoacoustics and…, 2380

Using a convolution model of the eCAP, additional information about the neural firing properties can be obtained, which may provide relevant information about the health of the auditory nerve. … For most eCAPs, the estimated nerve firing probability was bimodal and could be parameterised by two Gaussian distributions with an average latency difference of 0.4 ms. — Dijk, Pim van, Physiology, Psychoacoustics and…, 2379

Categorization

• DEFINE: Defines eCAP and introduces the convolution model approach that lets firing properties be extracted from the compound potential.
• XREF: Connects to compound action potential biology and cochlear implant electrophysiology beyond van Dijk’s perceptual focus.
• corroborated: 2 independent passages support this claim — Dijk, Pim van, Physiology, Psychoacoustics and…, 2380; Dijk, Pim van, Physiology, Psychoacoustics and…, 2379