Cellular synaptic timing parameters determine a neuron’s preferred modulation frequency

Evidence

The band-enhanced model (Fig. 1 , BE) was Nelson and Carney’s ( 2004 ) same-frequency inhibitory-excitatory (SFIE) model. The key mechanism in this model is a dynamic interaction between relatively short-duration excitatory and relatively long-duration, delayed inhibitory synaptic potentials. The durations of the excitatory and inhibitory potentials and the delay of the inhibition with respect to the excitation determine the model’s best modulation frequency (BMF). — Dijk, Pim van, Physiology, Psychoacoustics and…, 5485

Categorization

• DEFINE: Defines the SFIE model and grounds best modulation frequency (BMF) in measurable synaptic timing parameters.