Brain activity drives opposing concentration changes in oxygenated and deoxygenated blood
Evidence
In response to neural activity in the brain, an increase in oxygenated blood is directed to the region, resulting in a drop in de-oxygenated blood. Thus HbO and HbR concentrations change in opposite directions in response to neural activity (Shah and Seghouane 2014 ). Changes in HbO and HbR resulting from a neural response to a stimulus or due to resting state activity can be analysed to produce activation patterns and also to derive connectivity measures between regions of interest. — Dijk, Pim van, Physiology, Psychoacoustics and…, 4282
Categorization
Category: Causal Relationships
- DEFINE: Explains the physiological basis (haemodynamic response) underlying fNIRS measurements — oxygenated vs deoxygenated blood moving in opposite directions.
Related
- Neural activity drives opposite changes in oxygenated and deoxygenated hemoglobin (similarity 0.89)
- Neural activity raises oxygenated and lowers de-oxygenated blood locally, enabling optical imaging (similarity 0.86)
- Brain activity can be measured optically because haemoglobin absorbs near-infrared light differently when oxygenated. (similarity 0.85)
- Oxygenated and deoxygenated haemoglobin absorb near-infrared light differently, enabling functional imaging (similarity 0.84)