The fundamental question of why there is something rather than nothing marks the limits of knowledge tied to limits of mind.

Evidence

What Are The Limits of Knowledge? (Philosophy Now)

corroborated: 2 independent passages support this claim
XREF: connects to: Human knowledge fails to answer life’s fundamental questions. — Leo Tolstoy, A Confession, 64; Human knowledge is limited and cannot answer why the universe exists or the purpose of life. — Science, Faith, and the Limits of Human Knowledge; Certain philosophical problems like the mind–body problem may be fundamentally unknowable by humans due to cognitive closure. — Cognitive closure (philosophy) (+11 more)

Human knowledge is limited and cannot answer why the universe exists or the purpose of life. (similarity 0.87)
Philosophy can only restate life’s fundamental questions. (similarity 0.86)
Knowledge becomes less clear as it approaches life’s big questions. (similarity 0.82)
Science cannot answer the fundamental questions of human existence. (similarity 0.80)
Knowing more sometimes shrinks the sense of the unknown rather than expanding it. (similarity 0.79)