Repeated early stress amplifies rather than dulls the stress-response system

Evidence

“Infants who had experienced harsh parenting showed elevated cortisol reactivity to the mild stressor — a pattern consistent with sensitization of the HPA axis. That is, the stress-response system of these infants was not dulled by repeated activation; it was amplified. Their cortisol responses were larger, not smaller, than those of infants from non-harsh-parenting households.” … Larger, not smaller. This is the opposite of what a naive hypothesis would predict. If you thought of the stress response as a muscle, you might expect that repeated activation would build tolerance — that children who experience frequent stress would become better at handling it. They don’t. Their systems become more reactive. More volatile. More easily triggered. The thermostat has been recalibrated — not upward toward resilience, but downward toward hypervigilance. — , The Rod and the Child, 5780

Categorization

  • SEED: Angle: the ‘stress builds character’ folk wisdom is neurologically backwards — repeated activation recalibrates the thermostat toward hypervigilance.
  • XREF: connects to: The stress response to corporal punishment is biologically invariant across cultures — , The Rod and the Child: A Global History…, 6565; Rearing behavior, not genetic sequence, determines adult anxiety in rat pups — , The Rod and the Child: A Global History…, 6777; ACE dose-response effects strengthen with higher baseline adversity in other populations — , The Rod and the Child: A Global History…, 7085 (+8 more)

Broader Connections