Depression is distinguished by its two constitutive questions
Evidence
We can act on nature, albeit the psychic kind, and not only on sickness and hereditary dysfunctions, which we used to suffer through the best we could. References have changed for living beings, but psychiatry’s problem is that these illnesses are “special.” They concern the potential uses of the notion of personality via two questions that underpin the biological, medical, and psychopathological history of depression: what are we treating? Whom are we curing? — Alain Ehrenberg, The Weariness of the Self, 921