Deconvolution of neural responses inherently amplifies high-frequency noise

Evidence

Having assumed the same unit response for all contributing fibres, the CDLD can be obtained directly from the recorded eCAP by deconvolution. The deconvolution was performed in the frequency domain with (4) where represents the Fourier transform and the inverse Fourier transform. … The deconvolution of the eCAP can be understood as applying an inverse low-pass filter, amplifying unwanted high-frequency noise. Therefore, the extrapolated eCAPs were low-pass filtered by a 50-point moving-average filter applied twice (once in forward and once in reverse direction) to achieve a zero-phase digital filtering. — Dijk, Pim van, Physiology, Psychoacoustics and…, 2402

Categorization

• DEFINE: Explains why deconvolution acts as an inverse low-pass filter and the consequent noise-amplification trade-off.