Certain philosophical problems like the mind–body problem may be fundamentally unknowable by humans due to cognitive closure.

Evidence

Cognitive closure (philosophy) (Wikipedia)

Categorization

• corroborated: 2 independent passages support this claim
• XREF: connects to: Life is full of unfathomable mysteries that elude understanding. — Crews, Harry, A childhood the biography of a place, 374; Humans, like every other animal, are not smart enough to understand all of nature’s laws, and unknowable unknowns may vastly exceed what we can ever know. — Mysterianism; If a truth depends on more truths than the knower can know, it is accidentally unknowable, not inherently so. — Could there be an (in principle) unknowable truth? (+16 more)

Related

• Humans, like every other animal, are not smart enough to understand all of nature’s laws, and unknowable unknowns may vastly exceed what we can ever know. (similarity 0.83)
• If a truth depends on more truths than the knower can know, it is accidentally unknowable, not inherently so. (similarity 0.83)
• Philosophy can only restate life’s fundamental questions. (similarity 0.78)

Broader Connections

• The feeling that systematic knowledge is impossible stems from uncontrollable modern events, not epistemology #contradicts (0.78) — Anthony Giddens, The Consequences of Modernity, 19